Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Mixed dust pneumoconiosis with asbestosis (Silicoasbestosis)
- Radiologic Findings
- Fig 1. Chest PA shows small nodular densities in both lungs and focal reticular densities in RLL costophrenic angle area.
Fig 2-4. CT scans reveals a 37 mm conglomerated mass with internal high-density calcification in RUL, and multiple well defined small nodular density in BUL zone and BML zone. In addition, multifocal discontinuous calcified and noncalcified plaques in both hemithorax, prominent in posterior portion, and reticular density, ground-glass opacity (GGO) with subpleural dots in both lower lung subpleural portion. Several small lymph node calcifications in mediastinum and right hilum.
- Brief Review
- Occupational lung diseases are a broad group of diagnosis caused by the inhalation of dusts, chemicals, or proteins. Pneumoconiosis is the term used for the diseases associated with inhaling inorganic particles and mineral dust. The severity of the disease is related to the material inhaled and the intensity and duration of the exposure.
Most pneumoconiosis is due to a single stimulus, but two or more different minerals concomitantly responsible for pulmonary disease constitute mixed dust pneumoconiosis (MDP). Anthraco-silicosis and silico-siderosis are main examples of mixed dust exposures which can occur from an exposure to a dust mixture in which the patient has inhaled two different particle types concurrently. There may also be the combination of silicosis and siderosis, the combination of aluminosis and silicosis, the combination of argyria and siderosis, and combinations of other mineral dusts include talc with asbestos, talc with silica, and talc with kaolin. In rare cases, an individual patient may have both asbestos and silicosis or mixed dust pneumoconiosis.
Radiologic findings may help to differentiate mixed dust pneumoconiosis and to distinguish classic silicosis. The classic chest X-ray pattern of MDP is a bilateral mixture of irregular or reticular opacities with small rounded nodules, as defined by the ILO classification. However, the findings depend on the component proportions of the mixed dust and the cumulative exposure history. Chest CT may show a reticular, reticulonodular or nodular pattern with emphysema and honeycombing. In exceptional cases, however, in which MDP is present together with another well-defined pneumoconiosis such as asbestosis, the diagnosis mixed dust pneumoconiosis or MDP with, for example, asbestosis might be made.
- Please refer to
Case 23, Case 546, Case 591, Case 1091, -
KSTR imaging conference 2018 Spring Case 11
,
KSTR Imaging Conference 2014 Spring Case 7
,
KSTR Symposium 1998 Case 11,
- References
- 1. ILO Classification of Radiographs of Pneumoconiosis. International Labor Office. Geneva: ILO Publications, 1980.
2. Gene J. Mark, Carl B. Monroe, Homayoun Kazemi. Mixed Pneumoconiosis. Chest ,1979; Volume 75, Issue 6, Pages 726
- Keywords
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lung, mixed dust pneumoconiosis, asbestosis, silicosis, silicoasbestosis,